CAMBRONNE LAB
Recent Publications:
SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells.
Mu-Jie Lu, Jonathan Busquets, Valeria Impedovo, Crystal N. Wilson, Hsin-Ru Chang, William Matsui, Stefano Tiziani, Xiaolu A. Cambronne.
Cell Metabolism (2024)
Layered mechanisms regulating the human mitochondrial NAD+ transporter SLC25A51.
Shivansh Goyal & Xiaolu A. Cambronne.
Biochemical Society Transactions (2023)
Dynamics of SLC25A51 reveal preference for oxidized NAD+ and substrate led transport.
Shivansh Goyal, Akhilesh Paspureddi, Mu-Jie Lu, Hsin-Ru Chan, Scott N Lyons, Crystal N Wilson, Marc Niere, Mathias Ziegler, Xiaolu A. Cambronne.
EMBO Reports (2023)
A chemical solution for FRET(ful) pairs.
Scott N. Lyons & Xiaolu A. Cambronne.
Nature Chemical Biology (2023)
Improved Yield for the Enzymatic Synthesis of Radiolabeled Nicotinamide Adenine Dinucleotide.
Jared Eller, Shivansh Goyal, Xiaolu A. Cambronne.
ACS Bio & Med Chem Au (2023)
The mitochondrial NAD+ transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions.
Zhiyao Fu, Hyunbae Kim, Paul T Morse, Mu-Jie Lu, Maik Hüttemann, Xiaolu A. Cambronne, Kezhong Zhang, Ren Zhang.
Metabolism, volume 135 (2022)
SLC25A51 is a mammalian mitochondrial NAD+ transporter.
Timothy S. Luongo, Jared M. Eller, Mu-Jie Lu, Marc Niere, Fabio Raith, Caroline Perry, Marc R. Bornstein, Paul Oliphint, Lin Wang, Melanie R. McReynolds, Marie E. Migaud, Joshua D. Rabinowitz, F. Brad Johnson, Kai Johnsson, Mathias Ziegler, Xiaolu A. Cambronne, Joseph A. Baur.
Nature, volume 588, pages 174–179 (2020)
Xiaolu A. Cambronne & W. Lee Kraus.
Trends in Biochemical Sciences, volume 45 issue 10, Pages 858-873 (2020)
Flow Cytometry Analysis of Free Intracellular NAD+ Using a Targeted Biosensor.
Jared M. Eller, Melissa L. Stewart, Alexandria J. Slepian, Sheila Markwardt, Jack Wiedrick, Michael S. Cohen, Richard H. Goodman, Xiaolu A. Cambronne.
Current Protocols in Cytometry, volume 88, issue 1, e54 (2019)
Methods for Using a Genetically Encoded Fluorescent Biosensor to Monitor Nuclear NAD+.
Michael S. Cohen, Melissa L. Stewart, Richard H. Goodman, Xiaolu A. Cambronne.
Methods in Molecular Biology, volume 1813, pages 391-414 (2018)
Biosensor reveals multiple sources for mitochondrial NAD⁺.
Xiaolu A. Cambronne, Melissa L. Stewart, DongHo Kim, Amber M. Jones-Brunette, Rory K. Morgan, David L. Farrens, Michael S. Cohen, Richard H. Goodman.
Science, volume 352, issue 6292, pages 1474-1477 (2016)